New Discovery May Lead to New Fibroid Treatment

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A recent study released but the University of Helsinki may eventually lead to early intervention in treating fibroids. After examining fibroids from a large sample of women 70 % contained a single gene mutation, MED12, which may lead to the ability to treat this condition.

"This is a giant step toward understanding why fibroids arise -- but toward design of targeted therapies it is a very early step," study leader Lauri A. Aaltonen, MD, PhD, of the University of Helsinki, says in a news release. "Let's hope that this journey has begun."

Fibroids, also called leiomyomas, are noncancerous growths of the uterus. Up to 60% of women develop fibroids by age 45. In many cases these growth go undetected and cause no problems, however for some women they can cause painful periods, irregular bleeding and are a factor in recurrent miscarriage.

Current treatments for problem fibroids are most often focused on symptom control with medication or removal of fibroids by a minimally invasive surgery called hysteroscopy. Recent discoveries of genetic mutations in fibroid tissue may lead to new treatments in that could reduce or eliminated with gene therapies.
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